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Tumor Necrosis Factor (TNF) is a pivotal inflammatory mediator regulated by epigenetic mechanisms and microRNAs

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Importantly, no large, definitive trial has yet established the efficacy of TPE in SAH, though a randomized study comparing TPE with SOC is currently recruiting (NCT06355726) [72]

GHK-Cu acts as a genomic modulatorit can upregulate a broad array of genes related to tissue growth and downregulate those linked to inflammation and tissue breakdown [1]